Description
SELANK
| CAS Number | 129954-34-3 |
| Alias | Thr-Lys-Pro-Arg-Pro-Gly-Pro TP-7 Tuftsin analog |
| IUPAC Name | L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolyl-glycyl-L-proline |
| Molecular Formula | C33H57N11O9 |
| Molecular Weight | 751.88 g/mol |
Selank (Thr–Lys–Pro–Arg–Pro–Gly–Pro)
Selank is a synthetic heptapeptide derived from the immunomodulatory tetrapeptide tuftsin. It is commonly used in in vitro and in vivo experimental research focused on peptide-monoamine interactions, neurochemical modulation, and neuroimmune signaling pathways. Due to its structural origin and unique sequence, Selank is frequently investigated in models exploring central nervous system regulation and immune-neural interface dynamics.
Mechanistic Pathways (Experimental Use Only)
Monoaminergic Modulation
Selank has been studied for its influence on serotonin and dopamine pathways in neural tissue models. Research focuses on its regulatory potential within circuits associated with cognitive focus, emotional balance, and stress-related signaling.
GABAergic System Studies
Research using electrophysiological and molecular models has explored Selank’s potential interaction with the GABAergic system, particularly its ability to modulate inhibitory tone and maintain neuronal stability under excitatory conditions.
Immunomodulatory Research
As a tuftsin-derived peptide, Selank is also used in preclinical studies involving cytokine expression, immune-neural signaling, and neuroinflammation models under experimentally controlled conditions.
Stress Management and Emotional Balance Benefits
Selank provides natural support for stress response and emotional well-being. The peptide helps regulate stress hormones while promoting a calm, focused mental state. Users often experience reduced anxiety levels and improved mood stability during challenging periods. The gentle action supports your body’s ability to handle daily pressures without unwanted side effects. Regular use may contribute to better sleep quality and overall stress resilience. This makes it valuable for professionals, students, and anyone managing high-stress environments.





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